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MYP_156393
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Basic Information
PSPHa
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
19 amino acids
C92H144N22O24
Standard
Sequence
FLSLIPAAISAVSALANHF
Physicochemical Analysis
1942.26 Da
6.74
-0.15
-0.41
-0.0080
1.50
0.39
0.57
12.64
144.21
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
710.79
-5.08
24.0
25.0
58.0
138.0
4.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0207051 VERIFIED: YES
Provenance & Taxonomy
Pithecopus hypochondrialis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
512 μM
MIC
PMID30774309 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30774309/
RECORD: Rec_0208292 VERIFIED: YES
Provenance & Taxonomy
Pithecopus hypochondrialis [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HCT 116
36.64 μM
LD50
PaperPubMed PMID: 28850103 PMID28850103 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28850103/
RECORD: Rec_0239382 VERIFIED: YES
Provenance & Taxonomy
Pithecopus hypochondrialis [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
PC-3
37.96 μM
LD50
PaperPubMed PMID: 28850103 PMID28850103 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28850103/
RECORD: Rec_0248401 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa hypochondrialis [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus NCTC 10788
8 μg/mL
MIC
PMID28850103 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28850103/
RECORD: Rec_0255756 VERIFIED: YES
Provenance & Taxonomy
Pithecopus hypochondrialis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
32 μM
MIC
PMID30774309 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30774309/
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