Peptide Database

Peptide NameUnnamed

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC38H58N12O12

DescriptionStandard

        LNFDPNR
    

Molecular Weight874.94 Da

Isoelectric Point (pI)5.84

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0341

GRAVY Index-1.43

Hydrophobic Moment 0.30

Boman Index-0.37

Instability Index4.73

Aliphatic Index 55.71

Aromaticity 0.1429

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 414.51

LogP -4.41

H-bond Donors 13.0

H-bond Acceptors 12.0

Rotatable Bonds 26.0

Heavy Atoms 62.0

Ring Count 2.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0263517 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory DPP-IV inhibitory Antidiabetic

TargetACE; DPP-IV

PaperIdentification of in vitro angiotensin-converting enzyme and dipeptidyl peptidase IV inhibitory peptides from draft beer by virtual screening and molecular docking. Journal of the Science of Food and Agriculture 102:1085-1094 (2022). PMID: 34309842. PMID34309842 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34309842/

RECORD: Rec_0362615 VERIFIED: YES