Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length1019 amino acids

Chemical FormulaC4790H7663N1357O1508S18

DescriptionStandard

        MSGGDGQGHNSGAQSTGGVNGTAGPGGTSSGGGVDASDHSGWSSENNPWGGGSGSGVHWGGGSGNGNNGGQTGGSSSGVNLSLFPEAQASVAFGAPMNISLIDGMWGFSVFRASTVQEAVAAALAKLDQSLISALPYVGRLAGAMFGLLIPSSIAPDDTSMMSQIVTTLPAARVMDAPVSTLPTQLATVTVHTRITDIVQNERQHLAVVGGIPANVPVVDAKPTARAGVFTAAVVPGLPDIHIRTEMGTPVAVSPAKGVTPENADARPAGFTAGGNSHEAIIRFPKESGQEPIYVSVTRPLTPEQVKQRQEEENRLQQAWNDAHPVEASREKEYLAGVALDFANQETARRREAVIHLKNTPEGLTLSNPELHPHTFVRPHRRIVSGAYDYALSPATLVINTFSTLGRLIDGGPEALYNKPTEDIKGAFQQWQYLVEDLTTIRTTFQLAEKAIADAEKQVQLQVETVKQKGLELVAAQNAVRAAIKKEADRRAAEAKKQSDAVQEQFNADMLRLKQEEQERANKKYAYMVNYAVTVKKVIDDSKHLTAQEKNSLTDEVDILLLVGQAADTLKGVDIPCGKLDVIWLHVQNTDKQRKKEAEDAVIRARLAEAGVALAPTYTPEMVKAADILMAAPGALVLNRAIGLWAIQSGQAGYGVMTLPKNVSSDLDSVVGQSTNALPRFTIKGAPAITAAHLSYLTEIEDVGHHPVSILAISPRRLVSNKTIIEPGMAVVEMPVRGHLVEKDGRTVLELLATGDSIPKAVPVLNAERDASTGLDRITVPAVGSAPSLTILINPAPSPAKPSNTGNQSAFPVTPVHTGTEVIRPDKIVTTTTPTGDISSLQDFIYWQPDGAGTGVEPVYVMLSNPYGKTNAKGKYSGRDYNTEKAGGPIQNLDWKGASIDRAGVDKVKLHTGRFESTPENAVMIDRLEKILKSELQVTDTDKRYYTHEIREFERYRNLGIKDGEVPKSVQEQKAVWNNTHTATLEDYKINEKEQALYTDDALQAAYEQELKDALGGIK
    

Molecular Weight108966.44 Da

Isoelectric Point (pI)5.74

Net Charge (pH 7.0)-16.43

Net Charge (pH 7.4) -18.04

Charge Density (pH 7.0) -0.0161

GRAVY Index-0.31

Hydrophobic Moment 0.78

Boman Index0.02

Instability Index37.93

Aliphatic Index 85.42

Aromaticity 0.0530

Extinction Coeff. Reduced 96260.00

Extinction Coeff. Oxidized 96260.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0160438 VERIFIED: YES

Provenance & Taxonomy

OrganismYersinia frederiksenii [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)