Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length524 amino acids

Chemical FormulaC2486H3905N751O769S18

DescriptionStandard

        MGYRSTNYGRGQALHGDRTTTGAICCSTLPNCTEHGRGVIRVGDKTTACPKCGKQGVVAEGEPRVNWMGQTSAVDGSVVICGCPHGTNRVIAPSGEWLGSGPSPEQIAQEKHQAMLAARRKEQEAEAQRQAEERDRNRVFAKSCLRGEGCNDAGTGSEPHTNFAEMAFYQAIPNNAPQHAQAAKRKALPKPKQRSALYLWWNGHHEEMDYQAAVAAEERAWTARTAIADASELVLVGGRTVISGTWAVRGAALGGIATGGLGAPVAGLLIGMYPGKLNDGEQDFIDRMRVEQMREAPTRVRFTWENDASGNPTPRGWHTPPGKDSVRVRTMEWDSRRQAYTFTTEENPGITLIWTPDRTGESKPWDTGNHNPVRIPNPVVVDPLPEDTGIGATTSPTPEEKTFADYILILPVGGVPPIYVYLSGKRRSGLPEDGHDYHQAPKTSEITGLSGLREVKAKTPKQGGSGKRARWVDSKGRRIYEWDSQHGELEEYRASDGEHLGSIDYKTGEILKPAVKGRNIKSYL
    

Molecular Weight57194.34 Da

Isoelectric Point (pI)8.27

Net Charge (pH 7.0)3.73

Net Charge (pH 7.4) 2.53

Charge Density (pH 7.0) 0.0071

GRAVY Index-0.69

Hydrophobic Moment 0.74

Boman Index-0.09

Instability Index39.31

Aliphatic Index 63.17

Aromaticity 0.0668

Extinction Coeff. Reduced 93850.00

Extinction Coeff. Oxidized 94350.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0193719 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterobacter cloacae [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)