Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length582 amino acids

Chemical FormulaC2686H4254N802O873S10

DescriptionStandard

        MSGGDGIGHSSGAHATGGVNGSSSGSGGSSSGGGNNPNSGPGWGTTHTPNGDIHNYNPGEFGGGGHKPGGNSGNHDSGSGNGQPSGTVMAFGFPALAPAGAGGLAVTVSGDALAAAIADVLAALKGPFKFGTWGIALYGIMPTEIAKDDPSMMSKIVTSLPVDTVTESPVSSLPLDQATVSVTKRVTDVVKDERQHIAVVAGVPMSVPVVDAKPTNTPGVFSATVPGLPALEVSTGKDIPASTALPRGITEDKDRTERPAGFTFGGSSHEAVIRFPKESGQAPVYVSVTDVLTPEQVKQRQEEENRRQQEWDATQPVEVAERNYRLASDELNRANADVTGKQERQAQAGQAVAARKGELDAANKTFAEAKEEIKKFERFAHDPMAGGHRMWQMAGLKAQRAQNEVNQKQVEFNAAEKEKADADAALNEALENRKQKEQKAKDTKDKLDKENKRNQSGTATGQGQPVGDKWLEDASKEAGAPVPDRIADKLRGKEFRDFDDFRKKFWEEVSKDPELRKQFRKNNQKLIEKGNAPYPVPEEQVGGRETFELHHVKPISQDGGVYDMDNLRVTTPKRHIDIHRGK
    

Molecular Weight62070.01 Da

Isoelectric Point (pI)6.12

Net Charge (pH 7.0)-6.17

Net Charge (pH 7.4) -7.26

Charge Density (pH 7.0) -0.0106

GRAVY Index-0.74

Hydrophobic Moment 0.75

Boman Index-0.10

Instability Index40.32

Aliphatic Index 60.72

Aromaticity 0.0533

Extinction Coeff. Reduced 41940.00

Extinction Coeff. Oxidized 41940.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0244015 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmonella enterica subsp. salamae [Bacterium]

FamilyColicin/Bacteriocin

Tax ID28901

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli