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MYP_156230
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Basic Information
Plectasin-derived peptide NZ2114 [N9Q,L13V,R14K], MP1102
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
40 amino acids
C191H280N54O54S6
Standard
Sequence
GFGCNGPWQEDDVKCHNHCKSIKGYKGGYCAKGGFVCKCY
Physicochemical Analysis
4388.99 Da
8.61
2.87
2.46
0.0718
-0.65
0.36
-0.03
21.69
26.75
0.1500
9970.00
10345.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1740.79
-18.60
65.0
65.0
143.0
305.0
10.0
42.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0057206 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on Plectasin variant [Synthetic]
Plectasin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
but not Escherichia coli. MIC: Staphylococcus aureus ATCC25923 or ATCC29213 or ATCC6538 or ATCC43300 and 20 MRSA clinical strains
0.004-0.23 μM
MIC
PaperIn vitro and in vivo characterization of a new recombinant antimicrobial peptide, MP1102, against methicillin-resistant Staphylococcus aureus.
RECORD: Rec_0060683 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
0.06 μM
MIC
PMID26921181;25620367;30863725 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26921181/
RECORD: Rec_0134919 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Streptococcus pneumoniae CVCC 2350
0.228 μM
MIC
PMID26921181;25620367;30863725 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26921181/
RECORD: Rec_0145816 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
0.06 μM
MBC
PMID26921181;25620367;30863725 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26921181/
RECORD: Rec_0164660 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Clostridium perfringens CVCC 2027
0.91 μM
MIC
PMID26921181;25620367;30863725 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26921181/
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