Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC428H681N123O135S15

DescriptionStandard

        MKTFWVAVVVAVVLTCICMEESSAVPVTEVPDEEEPMSNDYSLTEHEEPSDDSWMMPYSPRARRRRRKCKFCCNCCSNICQTCCTRRL
    

Molecular Weight10190.70 Da

Isoelectric Point (pI)5.35

Net Charge (pH 7.0)-2.49

Net Charge (pH 7.4) -2.92

Charge Density (pH 7.0) -0.0283

GRAVY Index-0.34

Hydrophobic Moment 0.43

Boman Index-0.12

Instability Index105.93

Aliphatic Index 56.36

Aromaticity 0.0682

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4156.74

LogP -45.02

H-bond Donors 156.0

H-bond Acceptors 149.0

Rotatable Bonds 329.0

Heavy Atoms 701.0

Ring Count 15.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0392882 VERIFIED: NO

Provenance & Taxonomy

OrganismDissostichus mawsoni [Animal]

FamilyHepcidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0422465 VERIFIED: NO