Peptide Database

Peptide NameLymphotoxin-alpha

Function Ontology

Anticancer ▸ tumor necrosis factor family

Immunology ▸ Immune modulation ▸ Cytokine modulation

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length171 amino acids

Chemical FormulaC856H1296N224O240S3

DescriptionStandard

        LPGVGLTPSAAQTARQHPKMHLAHSTLKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLSNNSLLVPTSGIYFVYSQVVFSGKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLLSSQKMVYPGLQEPWLHSMYHGAAFQLTQGDQLSTHTDGIPHLVLSPSTVFFGAFAL
    

Molecular Weight18661.00 Da

Isoelectric Point (pI)8.94

Net Charge (pH 7.0)2.63

Net Charge (pH 7.4) 1.90

Charge Density (pH 7.0) 0.0154

GRAVY Index-0.04

Hydrophobic Moment 0.49

Boman Index0.17

Instability Index45.84

Aliphatic Index 85.03

Aromaticity 0.1111

Extinction Coeff. Reduced 21430.00

Extinction Coeff. Oxidized 21430.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7266.74

LogP -74.62

H-bond Donors 246.0

H-bond Acceptors 255.0

Rotatable Bonds 583.0

Heavy Atoms 1323.0

Ring Count 45.0

Amide Bonds 186.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0146479 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Familytumor necrosis factor family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Cytokine Growth factor tumor necrosis factor family Host defense