Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC354H560N96O97S7

DescriptionStandard

        MKIHLLFFILFLLVTVLPAKRKYPQYGSLDLSKECIDGNGRCRNYCPENEVRIAYCIRPGTHCCLESEG
    

Molecular Weight7937.27 Da

Isoelectric Point (pI)8.26

Net Charge (pH 7.0)1.62

Net Charge (pH 7.4) 1.20

Charge Density (pH 7.0) 0.0235

GRAVY Index-0.03

Hydrophobic Moment 0.51

Boman Index0.03

Instability Index44.53

Aliphatic Index 94.64

Aromaticity 0.1014

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3093.43

LogP -24.28

H-bond Donors 113.0

H-bond Acceptors 108.0

Rotatable Bonds 260.0

Heavy Atoms 554.0

Ring Count 13.0

Amide Bonds 72.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0131342 VERIFIED: NO

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyDefensin

Tax ID9986

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence