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MYP_156174
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Basic Information
Bowman-Birk proteinase inhibitor peptide PE-BBI
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
17 amino acids
C82H136N22O20S2
Standard
Sequence
GALKGCWTKSIPPKPCK
Physicochemical Analysis
1814.22 Da
9.70
3.74
3.50
0.2198
-0.50
0.34
-0.03
0.28
51.76
0.0588
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
662.88
-5.48
24.0
26.0
56.0
126.0
5.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0161069 VERIFIED: YES
Provenance & Taxonomy
Pelophylax esculentus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human colon adenocarcinoma HKE3
50.2 μM
IC50
PMID30267012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30267012/
RECORD: Rec_0196850 VERIFIED: YES
Provenance & Taxonomy
Pelophylax esculentus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human colon adenocarcinoma DLD-1
50.1 μM
IC50
PMID30267012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30267012/
RECORD: Rec_0250402 VERIFIED: YES
Provenance & Taxonomy
Pelophylax esculentus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli NCTC 10418
PMID30267012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30267012/
RECORD: Rec_0258990 VERIFIED: YES
Provenance & Taxonomy
skin secretion of Pelophylax esculentus [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HCT 116
35.4 μM
IC50
PaperPubMed PMID: 30267012 PMID30267012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30267012/
RECORD: Rec_0272194 VERIFIED: YES
Provenance & Taxonomy
skin secretion of Pelophylax esculentus [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
DLD-1
50.1 μM
IC50
PaperPubMed PMID: 30267012 PMID30267012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30267012/
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