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MYP_156173
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Basic Information
Unnamed
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
5 amino acids
C29H42N6O8
Standard
Sequence
VPYPQ
Physicochemical Analysis
602.68 Da
5.49
-0.27
-0.48
-0.0534
-0.76
0.13
0.15
109.72
58.00
0.2000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
225.46
-0.78
6.0
8.0
13.0
43.0
3.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0036445 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
beta-Casein-derived
9606
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperNovel anti-oxidative peptides from enzymatic digestion of human milk | Tsopmo, A. et al. | DOI: 10.1016/j.foodchem.2010.11.146 Evidence URLhttps://www.uniprot.org/uniprotkb/P05814/entry
RECORD: Rec_0063439 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic DPP-IV inhibitory
Dipeptidyl peptidase IV
41.45
IC50
PaperZheng L., Xu Q., Lin L., Zeng X., Sun B., Zhao M. M.. In vitro metabolic stability of a casein-derived dipeptidyl peptidase-IV (DPP-IV) inhibitory peptide VPYPQ and its controlled release from casein by enzymatic hydrolysis. J. Agric. Food Chem., 67, 10604-10613, 2019.
RECORD: Rec_0145741 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperTsopmo A., Romanowski A., Banda L., Lavoie J. C., Jenssen H.. Novel anti-oxidative peptides from enzymatic digestion of human milk. Food Chem., 126, 1138-1143, 2011.
RECORD: Rec_0313194 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
DPPH assay
PaperAntioxidant activity of Yogurt peptides: Part 2 – Characterisation of peptide fractions
RECORD: Rec_0374420 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
beta-Casein-derived
9606
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
DPP-IV inhibitory Antidiabetic
Dipeptidyl peptidase-IV (DPP-IV)
41.45 μM
IC50
PaperIn Vitro Metabolic Stability of a Casein-Derived Dipeptidyl Peptidase-IV (DPP-IV) Inhibitory Peptide VPYPQ and Its Controlled Release from Casein by Enzymatic Hydrolysis | L.Zheng. et al. | DOI: 10.1021/acs.jafc.9b03164 Evidence URLhttps://www.uniprot.org/uniprotkb/P05814/entry
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