Peptide Database

Peptide NamePotassium channel toxin-like peptide

Function Ontology

Membrane / Ion-channel modulation ▸ Ion channel modulation

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length43 amino acids

Chemical FormulaC195H309N57O59S7

DescriptionStandard

        NEAVPTGGCPFSDFFCAKRCKDMKFGNTGRCTGPNKTVCKCSI
    

Molecular Weight4620.34 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)3.70

Net Charge (pH 7.4) 3.40

Charge Density (pH 7.0) 0.0861

GRAVY Index-0.37

Hydrophobic Moment 0.39

Boman Index-0.08

Instability Index35.12

Aliphatic Index 27.21

Aromaticity 0.0930

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1875.60

LogP -24.74

H-bond Donors 70.0

H-bond Acceptors 70.0

Rotatable Bonds 150.0

Heavy Atoms 318.0

Ring Count 7.0

Amide Bonds 45.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0351717 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii,Buthus martensii [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin Ion Channel Blocker Potassium Channel Blocker

TargetKv1

Activity0.00079 μM

MethodIC50