Peptide Database

Peptide NameTumor necrosis factor ligand superfamily member 6, soluble form

Function Ontology

Anticancer ▸ tumor necrosis factor family

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic

Standard StatusStandard

Sequence Length152 amino acids

Chemical FormulaC783H1208N202O224S9

DescriptionStandard

        QIGHPSPPPEKKELRKVAHLTGKSNSRSMPLEWEDTYGIVLLSGVKYKKGGLVINETGLYFVYSKVYFRGQSCNNLPLSHKVYMRNSKYPQDLVMMEGKMMSYCTTGQMWARSSYLGAVFNLTSADHLYVNVSELSLVNFEESQTFFGLYKL
    

Molecular Weight17323.77 Da

Isoelectric Point (pI)9.15

Net Charge (pH 7.0)5.09

Net Charge (pH 7.4) 4.61

Charge Density (pH 7.0) 0.0335

GRAVY Index-0.32

Hydrophobic Moment 0.59

Boman Index0.04

Instability Index44.98

Aliphatic Index 76.84

Aromaticity 0.1250

Extinction Coeff. Reduced 27390.00

Extinction Coeff. Oxidized 27515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6859.52

LogP -62.13

H-bond Donors 240.0

H-bond Acceptors 242.0

Rotatable Bonds 572.0

Heavy Atoms 1218.0

Ring Count 32.0

Amide Bonds 164.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0084895 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Familytumor necrosis factor family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide73-104

Bio-Activity Profile

Function

Cytokine Growth factor tumor necrosis factor family Growth factor signaling Angiogenic