MYP_156124
Scapularisin-5
Antimicrobial
Standard
38 amino acids
C173H262N58O50S6
Standard
GFGCPFDQGACHRHCQSIGRRGGYCAGIIKQTCTCYHN
4146.68 Da
8.68
2.96
2.51
0.0779
-0.42
0.72
-0.03
89.34
36.05
0.1053
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1739.80
-22.88
67.0
62.0
132.0
287.0
8.0
41.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0007292
VERIFIED: NO
Provenance & Taxonomy
Ixodes scapularis [Animal]
6945
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0158873
VERIFIED: YES
Provenance & Taxonomy
Ixodes scapularis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
RECORD: Rec_0170120
VERIFIED: YES
Provenance & Taxonomy
Ixodes scapularis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
APD analysis reveals that this sequence is similar (97.37%) to Scapularisin-6 C: 16%, G: 18%. GRAVY: -0.42; mol Wt: 4146.741; mol formula: C173H263N57O50S6; mol ex coeff: 3355. Chemical modification: 3 disulfide bonds
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
0.38-2.0 μM
MIC
RECORD: Rec_0366186
VERIFIED: YES
Provenance & Taxonomy
Ixodes scapularis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
APD analysis reveals that this sequence is similar (97.37%) to Scapularisin-6 C: 16%, G: 18%. GRAVY: -0.42; mol Wt: 4146.741; mol formula: C173H263N57O50S6; mol ex coeff: 3355. Chemical modification: 3 disulfide bonds
Bio-Activity Profile
Antimicrobial
Staphylococcus epidermidis
1 μM
MIC