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MYP_156110
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Basic Information
Ranatuerin-4
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
24 amino acids
C126H206N30O28S2
Standard
Sequence
FLPFIARLAAKVFPSIICSVTKKC
Physicochemical Analysis
2653.30 Da
9.85
3.74
3.50
0.1557
1.11
0.65
0.30
34.61
117.92
0.1250
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
915.69
-4.23
34.0
34.0
84.0
186.0
5.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0261924 VERIFIED: YES
Provenance & Taxonomy
Lithobates catesbeiana [Animal]
Ranatuerin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
18-24
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
55 μM
MIC
PMID9784389 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9784389/
RECORD: Rec_0274789 VERIFIED: NO
Provenance & Taxonomy
Lithobates catesbeianus [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Amphibian defense peptide Antibiotic Antimicrobial Hemolytic Non-ribosomal
Qualitative functional evidence
PMID9784389 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9784389/; https://www.uniprot.org/uniprotkb/P82819/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0274992 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0276314 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0295658 VERIFIED: YES
Provenance & Taxonomy
Lithobates catesbeiana [Animal]
Ranatuerin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
18-24
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Hemolytic
human red blood cell
PMID9784389 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9784389/
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