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MYP_156110
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Basic Information
Ranatuerin-4
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
24 amino acids
C126H206N30O28S2
Standard
Sequence
FLPFIARLAAKVFPSIICSVTKKC
Physicochemical Analysis
2653.30 Da
9.85
3.74
3.50
0.1557
1.11
0.65
0.30
34.61
117.92
0.1250
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
915.69
-4.23
34.0
34.0
84.0
186.0
5.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002022 VERIFIED: YES
Provenance & Taxonomy
Rana catesbeiana [Animal]
Ranatuerin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
55 μM
MIC
PMID9784389 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9784389/
RECORD: Rec_0108019 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 41.7%, E 0.0%, T 29.2%, C 29.2% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-negative
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0136110 VERIFIED: YES
Provenance & Taxonomy
Rana catesbeiana [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
18-24
Disulfide bridge: C18,C24;
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
55 μM
MIC
PaperRanatuerins: antimicrobial peptides isolated from the skin of the American bullfrog, Rana catesbeiana.
RECORD: Rec_0198701 VERIFIED: NO
Provenance & Taxonomy
Rana catesbeiana [Animal]; Lithobates catesbeianus [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Hormone
RECORD: Rec_0251313 VERIFIED: YES
Provenance & Taxonomy
Lithobates catesbeiana [Animal]
Ranatuerin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
18-24
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Hemolytic
PMID9784389 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9784389/
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