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MYP_156071
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Basic Information
Cecropin-B1a, [Cecropin-B (1-10)]2-AGP-Cecropin-B (1-10)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
33 amino acids
C208H335N51O40
Standard
Sequence
KWKVFKKIEKKWKVFKKIEKAGPKWKVFKKIEK
Physicochemical Analysis
4190.20 Da
10.44
11.75
11.52
0.3562
-1.13
0.79
-0.31
20.54
64.85
0.1818
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1535.30
-1.39
54.0
52.0
154.0
299.0
10.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0073527 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human lung carcinoma NCI-H520
22.7
IC50
PMID19428759 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19428759/
RECORD: Rec_0108424 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0120009 VERIFIED: YES
Provenance & Taxonomy
Not available [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
NIH 3T3
50 μM
IC50
PaperPubMed PMID: 19428759 PMID19428759 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19428759/
RECORD: Rec_0164432 VERIFIED: YES
Provenance & Taxonomy
Not available [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
NCI-H520
22.7±0.2 μM
IC50
PaperPubMed PMID: 19428759 PMID19428759 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19428759/
RECORD: Rec_0168859 VERIFIED: YES
Provenance & Taxonomy
Not available [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
RPMI-7666
100 μM
IC50
PaperPubMed PMID: 19428759 PMID19428759 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19428759/
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