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MYP_156065
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Basic Information
Aurein 1.1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Enzyme modulation ▸ Enzyme inhibition ▸ nNOS inhibitor
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
13 amino acids
C68H115N15O19
Standard
Sequence
GLFDIIKKIAESI
Physicochemical Analysis
1446.73 Da
6.07
-0.24
-0.45
-0.0183
0.80
0.73
0.31
20.48
157.69
0.0769
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
559.39
-2.07
19.0
19.0
51.0
102.0
1.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0226607 VERIFIED: YES
Provenance & Taxonomy
Ranoidea raniformis [Animal]
116057
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Lactococcus lactis
25 μg/mL
MIC
PaperThe antibiotic and anticancer active aurein peptides from the australian bell frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2.
RECORD: Rec_0235787 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Anti-Gram-positive
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0246069 VERIFIED: YES
Provenance & Taxonomy
Ranoidea raniformis [Animal]
116057
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Streptococcus uberis
100 μg/mL
MIC
PaperThe antibiotic and anticancer active aurein peptides from the australian bell frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2.
RECORD: Rec_0264789 VERIFIED: YES
Provenance & Taxonomy
Ranoidea raniformis [Animal]
Frog skin active peptide (FSAP); Aurein subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-positive Non-hemolytic
Listeria innocua
PMID10951191;11784303 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10951191/
RECORD: Rec_0271045 VERIFIED: NO
Provenance & Taxonomy
Ranoidea raniformis [Animal]
Aurein
116057
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Not included yet
Amidation
Bio-Activity Profile
Antimicrobial
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