Peptide Database

Peptide NameRac2

Function Ontology

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length189 amino acids

Chemical FormulaC947H1505N249O278S9

DescriptionStandard

        MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRAC
    

Molecular Weight21115.17 Da

Isoelectric Point (pI)7.52

Net Charge (pH 7.0)0.62

Net Charge (pH 7.4) 0.15

Charge Density (pH 7.0) 0.0033

GRAVY Index-0.16

Hydrophobic Moment 0.67

Boman Index0.02

Instability Index39.47

Aliphatic Index 91.80

Aromaticity 0.0847

Extinction Coeff. Reduced 22920.00

Extinction Coeff. Oxidized 23295.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8438.07

LogP -97.42

H-bond Donors 295.0

H-bond Acceptors 290.0

Rotatable Bonds 689.0

Heavy Atoms 1483.0

Ring Count 33.0

Amide Bonds 201.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0376654 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsLysine residue at position 147 is N6-acetyllysine; C-terminal cysteine residue undergoes lipidation to become S-geranylgeranyl cysteine

Bio-Activity Profile

Function

Signaling peptide

TargetPLCβ2 (Human); PLCγ2 (Human)