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MYP_156062
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Basic Information
Phormicin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
40 amino acids
C163H270N58O52S6
Standard
Sequence
ATCDLLSGTGINHSACAAHCLLRGNRGGYCNGKGVCVCRN
Physicochemical Analysis
4066.63 Da
8.69
2.91
2.53
0.0727
0.05
0.53
0.03
14.48
73.25
0.0250
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1778.11
-26.55
69.0
63.0
133.0
279.0
3.0
43.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0393166 VERIFIED: YES
Provenance & Taxonomy
Phormia terranovae [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
B. thuringiensis 53137
PMID2911573 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2911573/
RECORD: Rec_0396339 VERIFIED: YES
Provenance & Taxonomy
Black blowfly [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
cells, Micrococcus luteus
PaperInsect immunity: isolation from immune blood of the dipteran Phormia terranovae of two insect antibacterial peptides with sequence homology to rabbit lung macrophage bactericidal peptides.
RECORD: Rec_0419317 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0422403 VERIFIED: NO
Provenance & Taxonomy
Phormia terraenovae [Animal]
Defensin
Structure & Mods
linear disulfide-stabilized peptide [Linear]
canonical L-amino-acid peptide [L]
3-30, 16-36, 20-38
Bio-Activity Profile
Antimicrobial Antibacterial
Phormia terraenove
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