Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC318H517N101O89S9

DescriptionStandard

        RCRKACWVIRGHCRKYCKSGERVKKPCNNGDYCCTVSRMDTLPQAPTKNFKNSKTPPVMVFLSNN
    

Molecular Weight7467.72 Da

Isoelectric Point (pI)9.81

Net Charge (pH 7.0)10.77

Net Charge (pH 7.4) 10.40

Charge Density (pH 7.0) 0.1657

GRAVY Index-0.79

Hydrophobic Moment 0.75

Boman Index-0.27

Instability Index27.26

Aliphatic Index 43.38

Aromaticity 0.0769

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3121.63

LogP -37.17

H-bond Donors 116.0

H-bond Acceptors 110.0

Rotatable Bonds 246.0

Heavy Atoms 517.0

Ring Count 12.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0228398 VERIFIED: NO

Provenance & Taxonomy

OrganismCricetulus griseus [Animal]

FamilyDefensin

Tax ID10029

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal