Peptide Database

Peptide NameGlia-gamma30-gliadin (p222236; E225)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC70H116N20O23

DescriptionStandard

        VQGEGIIQPQQPAQL
    

Molecular Weight1605.79 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.26

Net Charge (pH 7.4) -1.48

Charge Density (pH 7.0) -0.0842

GRAVY Index-0.41

Hydrophobic Moment 0.31

Boman Index0.12

Instability Index62.85

Aliphatic Index 104.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 705.89

LogP -7.53

H-bond Donors 20.0

H-bond Acceptors 22.0

Rotatable Bonds 52.0

Heavy Atoms 113.0

Ring Count 2.0

Amide Bonds 19.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0372924 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E225

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman gluten-specific T cells / HLA-DQ2

MethodT-cell proliferation assay