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MYP_156020
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Basic Information
Temporin L [Q3P,R11Orn]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
13 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
FVPWFSKFLGXIL
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0034770 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 11
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 25923
12 μM
MIC
PMID21319749 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319749/
RECORD: Rec_0063541 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 11
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25922
12 μM
MIC
PMID21319749 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319749/
RECORD: Rec_0070316 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
8407.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
6 μM
Hemolysis
PaperMangoni ML, Carotenuto A, Auriemma L, et al. Structure-activity relationship, conformational and biological studies of temporin L analogues. J Med Chem. 2011 Mar 10;54(5):1298-1307. doi:10.1021/jm1012853. PMID21319749 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319749/
RECORD: Rec_0089252 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 11
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 15692
48 μM
MIC
PMID21319749 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319749/
RECORD: Rec_0094643 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 11
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Streptococcus pyogenes ATCC 21547
6 μM
MIC
PMID21319749 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319749/
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