Peptide Database

Peptide NamePotassium channel toxin MeuTXKbeta3-meucin-24

Function Ontology

Membrane / Ion-channel modulation ▸ Ion channel modulation

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length47 amino acids

Chemical FormulaC228H366N68O72S8

DescriptionStandard

        KMKNSWNRLTSMSEYACPVIEKWCEDHCQAKNAIGRCENTECKCLSK
    

Molecular Weight5468.28 Da

Isoelectric Point (pI)8.30

Net Charge (pH 7.0)1.80

Net Charge (pH 7.4) 1.44

Charge Density (pH 7.0) 0.0382

GRAVY Index-0.83

Hydrophobic Moment 0.54

Boman Index-0.22

Instability Index82.96

Aliphatic Index 45.74

Aromaticity 0.0638

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2314.17

LogP -26.22

H-bond Donors 86.0

H-bond Acceptors 83.0

Rotatable Bonds 187.0

Heavy Atoms 376.0

Ring Count 7.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0019193 VERIFIED: NO

Provenance & Taxonomy

OrganismMesobuthus eupeus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin Channel blocker