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MYP_156000
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Basic Information
DPKQDFMRF-amide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Standard
9 amino acids
C53H78N14O15S
Standard
Sequence
DPKQDFMRF
Physicochemical Analysis
1183.34 Da
5.96
-0.24
-0.44
-0.0265
-1.44
0.56
-0.39
39.80
0.00
0.2222
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
492.94
-3.37
16.0
16.0
38.0
83.0
3.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0018219 VERIFIED: NO
Provenance & Taxonomy
Drosophila virilis [Animal]
DPKQDFMRF-amide
7244
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide Neuromodulator Myotropic Receptor modulation
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
RECORD: Rec_0038277 VERIFIED: YES
Provenance & Taxonomy
Drosophila melanogaster [Animal]
FMRFamide-like peptide
7227.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Cardioactive Neuromodulatory
Drosophila melanogaster heart
Cardiac contractility assay
PaperPMID 24069424. Drosophila FMRFamide peptides (including DPKQDFMRFamide) modulate cardiac contractility via FMRFa-R. PMID24069424 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24069424/
RECORD: Rec_0085068 VERIFIED: NO
Provenance & Taxonomy
Drosophila melanogaster [Animal]; Drosophila suzukii [Animal]
7227
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide
RECORD: Rec_0208520 VERIFIED: NO
Provenance & Taxonomy
Drosophila virilis [Animal]
FMRFamide related peptide
7244
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
RFamide Neuropeptide Neuromodulator
Evidence URLhttps://www.uniprot.org/uniprotkb/FMRF_DROVI/entry
RECORD: Rec_0260059 VERIFIED: NO
Provenance & Taxonomy
Drosophila melanogaster [Animal]
FMRFamide related peptide
7227
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
RFamide Neuropeptide Neuromodulator
Evidence URLhttps://www.uniprot.org/uniprotkb/FMRF_DROME/entry
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