Peptide Database

Peptide NameMoronecidin (Piscidin-1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antiviral

Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length79 amino acids

Chemical FormulaC406H628N120O119S4

DescriptionStandard

        MKCATLFLVLSMVVLMAEPGDAFFHHIFRGIVHVGKTIHRLVTGGKAEQDQQDQQYQQEQQEQQAQQYQRFNRERAAFD
    

Molecular Weight9222.32 Da

Isoelectric Point (pI)6.39

Net Charge (pH 7.0)-1.14

Net Charge (pH 7.4) -1.60

Charge Density (pH 7.0) -0.0145

GRAVY Index-0.57

Hydrophobic Moment 0.73

Boman Index-0.08

Instability Index45.31

Aliphatic Index 70.38

Aromaticity 0.1013

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3930.04

LogP -38.62

H-bond Donors 132.0

H-bond Acceptors 126.0

Rotatable Bonds 315.0

Heavy Atoms 649.0

Ring Count 13.0

Amide Bonds 93.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0418530 VERIFIED: YES

Provenance & Taxonomy

OrganismMorone saxatilis [other]

FamilyPleurocidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Antiviral Anti-HSV Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetGram Negative Bacteria and Gram Positive Bacteria