Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC467H755N123O130S7

DescriptionStandard

        MKLFLVLIILLSEVPTDGARLKTCFNNITGYCRKKCKVGEIYEIGCLSGKLCCVNDEENKKHVPFKKPHTHSGEKSSIHQGYAILPTVTIFTV
    

Molecular Weight10397.19 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)4.79

Net Charge (pH 7.4) 4.26

Charge Density (pH 7.0) 0.0516

GRAVY Index-0.01

Hydrophobic Moment 0.56

Boman Index0.07

Instability Index30.80

Aliphatic Index 95.27

Aromaticity 0.0753

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4047.40

LogP -34.65

H-bond Donors 145.0

H-bond Acceptors 146.0

Rotatable Bonds 350.0

Heavy Atoms 727.0

Ring Count 15.0

Amide Bonds 97.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0036153 VERIFIED: NO

Provenance & Taxonomy

OrganismAotus nancymaae [Animal]

FamilyDefensin

Tax ID37293

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence