Peptide Database

Peptide NameNatriuretic peptide NP2

Function Ontology

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC146H242N48O45S2

DescriptionStandard

        VSTSRGSQGCFGLKLDRIGAASGLGCWRRIVDS
    

Molecular Weight3453.91 Da

Isoelectric Point (pI)9.69

Net Charge (pH 7.0)2.72

Net Charge (pH 7.4) 2.47

Charge Density (pH 7.0) 0.0823

GRAVY Index-0.01

Hydrophobic Moment 0.61

Boman Index-0.01

Instability Index32.04

Aliphatic Index 82.73

Aromaticity 0.0606

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1523.00

LogP -20.15

H-bond Donors 59.0

H-bond Acceptors 50.0

Rotatable Bonds 116.0

Heavy Atoms 241.0

Ring Count 3.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0135065 VERIFIED: YES

Provenance & Taxonomy

OrganismCrotalus durissus cascavella [Animal]

FamilyNatriuretic peptide NP2

Tax ID184540

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide10-26

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular

Half-LifeMammalian: 100 hour; Yeast: >20 hour; E. coli: >10 hour