Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC470H766N124O129S8

DescriptionStandard

        MKLFLVLIVLPFEVLPADTARPRKCFSNIIGYCRKKCEMGEIYEVACRNGKLCCVNEGENKKHKKAPKSPLFGQPDGKTDYVILPTTTLLTIQ
    

Molecular Weight10474.38 Da

Isoelectric Point (pI)9.11

Net Charge (pH 7.0)5.53

Net Charge (pH 7.4) 5.15

Charge Density (pH 7.0) 0.0595

GRAVY Index-0.13

Hydrophobic Moment 0.58

Boman Index0.01

Instability Index36.71

Aliphatic Index 90.11

Aromaticity 0.0753

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4058.26

LogP -32.66

H-bond Donors 143.0

H-bond Acceptors 144.0

Rotatable Bonds 350.0

Heavy Atoms 731.0

Ring Count 15.0

Amide Bonds 98.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0417501 VERIFIED: NO

Provenance & Taxonomy

OrganismPanthera leo [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence