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MYP_155776
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Basic Information
Fallaxidin 4.1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
21 amino acids
C106H172N26O24
Standard
Sequence
GLLSFLPKVIGVIGHLIHPPS
Physicochemical Analysis
2194.66 Da
8.76
0.93
0.63
0.0445
1.05
0.51
0.52
37.50
157.62
0.0476
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
742.79
-2.57
24.0
27.0
66.0
156.0
6.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0047861 VERIFIED: NO
Provenance & Taxonomy
Eastern dwarf [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0087153 VERIFIED: YES
Provenance & Taxonomy
Litoria fallax [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
L.lactis
12 μM
MIC
PMID18803332 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18803332/
RECORD: Rec_0128481 VERIFIED: YES
Provenance & Taxonomy
Litoria fallax [Animal]
Fallaxidin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperR.J. Jackway et al. / Rapid Communications in Mass Spectrometry 22 (2008) 3207-3216. The fallaxidin peptides from the skin secretion of the eastern dwarf tree frog Litoria fallax. Sequence determination by positive and negative ion electrospray mass spectrometry: antimicrobial activity and cDNA cloning of the fallaxidins Evidence URLhttps://www.uniprot.org/uniprotkb/B5LUQ4/entry
RECORD: Rec_0133941 VERIFIED: YES
Provenance & Taxonomy
Eastern dwarf tree [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
Bio-Activity Profile
Antimicrobial
Moderately active
12-100 μM
MIC
PaperThe fallaxidin peptides from the skin secretion of the Eastern Dwarf Tree Frog Litoria fallax. Sequence determination by positive and negative ion electrospray mass spectrometry: antimicrobial activity and cDNA cloning of the fallaxidins.
RECORD: Rec_0164987 VERIFIED: YES
Provenance & Taxonomy
Litoria fallax [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus epidermidis
100 μM
MIC
PMID18803332 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18803332/
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