Peptide Database

Peptide NameBrevinin-2TC

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC146H238N38O37S3

DescriptionStandard

        GLWESIKNLGKKFALNIMEKLKCKFGGGC
    

Molecular Weight3213.88 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.50

Charge Density (pH 7.0) 0.1290

GRAVY Index-0.09

Hydrophobic Moment 0.68

Boman Index0.08

Instability Index36.41

Aliphatic Index 84.14

Aromaticity 0.1034

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1231.04

LogP -8.51

H-bond Donors 44.0

H-bond Acceptors 44.0

Rotatable Bonds 115.0

Heavy Atoms 224.0

Ring Count 4.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0418076 VERIFIED: YES

Provenance & Taxonomy

OrganismRana amurensis [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)