Peptide Database

Peptide NameMidkine

Function Ontology

Binding / Molecular interaction ▸ Binding activity

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length123 amino acids

Chemical FormulaC578H939N179O169S10

DescriptionStandard

        VAKKKDKVKKGGPGSECAEWAWGPCTPSSKDCGVGFREGTCGAQTQRIRCRVPCNWKKEFGADCKYKFENWGACDGGTGTKVRQGTLKKARYNAQCQETIRVTKPCTPKTKAKAKAKKGKGKD
    

Molecular Weight13420.39 Da

Isoelectric Point (pI)9.78

Net Charge (pH 7.0)18.64

Net Charge (pH 7.4) 18.23

Charge Density (pH 7.0) 0.1515

GRAVY Index-1.04

Hydrophobic Moment 0.56

Boman Index-0.27

Instability Index10.57

Aliphatic Index 32.60

Aromaticity 0.0732

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5714.17

LogP -69.09

H-bond Donors 210.0

H-bond Acceptors 198.0

Rotatable Bonds 461.0

Heavy Atoms 936.0

Ring Count 19.0

Amide Bonds 130.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0384594 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Familypleiotrophin family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide17-41; 25-50; 32-54; 64-96; 74-106

Bio-Activity Profile

Function

Cytokine Growth factor pleiotrophin family Growth factor signaling Heparin-binding