Peptide Database

Peptide Namegamma-gliadin 1376 (p71-p90); gamma-gliadin M8 M36999 (71-80) homologous to DQ2-alpha-I and DQ2-gamma-IV

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC112H160N28O30

DescriptionStandard

        PFPQPQQTFPQQPQLPFPQQ
    

Molecular Weight2378.64 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.04

Net Charge (pH 7.4) -0.10

Charge Density (pH 7.0) -0.0021

GRAVY Index-1.39

Hydrophobic Moment 0.38

Boman Index-0.07

Instability Index169.75

Aliphatic Index 19.50

Aromaticity 0.1500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 914.44

LogP -8.65

H-bond Donors 24.0

H-bond Acceptors 30.0

Rotatable Bonds 66.0

Heavy Atoms 170.0

Ring Count 10.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0236932 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsReported substitutions/positions: M8; Reported substitutions/positions: M36999

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodIntestinal T-cell assay