Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length355 amino acids

Chemical FormulaC1762H2861N459O486S13

DescriptionStandard

        MSPCYWLALFALVPLTLATNPGVKVKLTDKGIDYSRMTIVNLGLPKSALVLVPGTGVSLAITNAFLSLHGNWTVRYLRFIRLYNLFKSYIDKALRSTLQKQICPLVADAIIDMNPQQNDQRYIIVCSSSLQVTAVKMSPCYWLALLALVPLTLAANPGVKVKLTDKGIEYGKQIGIASLQQKLKTIKVPDLSGTVKVPPIGKVKYSLTGMTIVNLELPKSALVLVPGTGVSLAITNAFINLHGNWKVRYFKFITDSGSFDLAVNGLTITASIAIKSDETGRPTVSSVNCVANIGRASIKFHGGASWLYNLFKSYIDKALRSTLQKQICPLVADAITDMNPHLKTLNGKTRLEGQM
    

Molecular Weight38668.19 Da

Isoelectric Point (pI)9.77

Net Charge (pH 7.0)20.78

Net Charge (pH 7.4) 20.19

Charge Density (pH 7.0) 0.0585

GRAVY Index0.25

Hydrophobic Moment 0.69

Boman Index0.16

Instability Index21.71

Aliphatic Index 112.59

Aromaticity 0.0761

Extinction Coeff. Reduced 45380.00

Extinction Coeff. Oxidized 45755.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0415566 VERIFIED: NO

Provenance & Taxonomy

OrganismCoregonus sp. `balchen` [Bacterium]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria