Peptide Database

Peptide NameCycloviolacin VY1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC139H227N39O44S6

DescriptionStandard

        CGESCVFIRCTITALLGCSCSNNVCYKNGLAP
    

Molecular Weight3340.91 Da

Isoelectric Point (pI)7.77

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) 0.41

Charge Density (pH 7.0) 0.0219

GRAVY Index0.62

Hydrophobic Moment 0.35

Boman Index0.20

Instability Index42.88

Aliphatic Index 85.31

Aromaticity 0.0625

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1332.50

LogP -17.20

H-bond Donors 52.0

H-bond Acceptors 51.0

Rotatable Bonds 106.0

Heavy Atoms 228.0

Ring Count 3.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0210373 VERIFIED: YES

Provenance & Taxonomy

OrganismCarapichea ipecacuanha [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)