Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC450H717N133O128S10

DescriptionStandard

        MCKSNLVGERYLFQQIVLEQLNIGKHHTLRCMGNTGICRPSCRKTEQPYLYCLNYQPCCLQSYMKISISVREEKNDWSQRNRWPKIS
    

Molecular Weight10358.97 Da

Isoelectric Point (pI)9.23

Net Charge (pH 7.0)6.61

Net Charge (pH 7.4) 6.16

Charge Density (pH 7.0) 0.0760

GRAVY Index-0.64

Hydrophobic Moment 0.55

Boman Index-0.16

Instability Index62.34

Aliphatic Index 72.76

Aromaticity 0.0920

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4296.54

LogP -43.00

H-bond Donors 156.0

H-bond Acceptors 147.0

Rotatable Bonds 348.0

Heavy Atoms 721.0

Ring Count 16.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0091378 VERIFIED: NO

Provenance & Taxonomy

OrganismUrsus americanus [Bacterium]

FamilyDefensin

Tax ID9643

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal