Peptide Database

Peptide Namealpha-Glia (p57p73; T65 and S73)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC92H136N22O26

DescriptionStandard

        QLQPFPQPTLPYPQPQS
    

Molecular Weight1966.20 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0142

GRAVY Index-1.15

Hydrophobic Moment 0.27

Boman Index-0.01

Instability Index163.66

Aliphatic Index 45.88

Aromaticity 0.1176

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 752.32

LogP -6.82

H-bond Donors 20.0

H-bond Acceptors 26.0

Rotatable Bonds 52.0

Heavy Atoms 140.0

Ring Count 8.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0243442 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsReported substitutions/positions: T65; Reported substitutions/positions: S73

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodT-cell proliferation assay