Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length446 amino acids

Chemical FormulaC2233H3517N601O617S14

DescriptionStandard

        TNPGFVVRITQAGLDYAHQHGITVLEKELAQLKLPDISGDFRLRHVAKVHYEISRLDLRSFHLPYSRISLVPNVGLQVAISNAFAEMDGNWRVKMYFIRDHGSFDLKVENVYIKINLKLGSDASGKPTIDTSDCSTRISKVRVHFSGKFGWLYNLFRSAIESRFRKILESKVCENVVSSVRNELQPYVRTLPVTARIDAMAGIDYSLVAPPTATAQSLDVDLKGEFFSLAHRSSVPFSPLALAFPPDHDRMVYFGASSYFFNTAGFAYHAAGALVFEITDSTVVSPRNGGLCRCPCPLPAPLQLEKMYPDTPMKLRLSASSAPFLNIGPGGLSLKPIVDIQAYAILPNSSQAPLFLLSLVSSGCAFRLVGAVPLGAKALFLPPLSPPQVRMLQSIMNVFASSILLPRLNARLDQGFPLPLPDRIQLSNILVRFHQVSEGELPALPR
    

Molecular Weight49103.38 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)10.33

Net Charge (pH 7.4) 9.41

Charge Density (pH 7.0) 0.0232

GRAVY Index0.11

Hydrophobic Moment 0.70

Boman Index0.11

Instability Index43.06

Aliphatic Index 100.36

Aromaticity 0.0919

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30745.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0151419 VERIFIED: NO

Provenance & Taxonomy

OrganismCalonectris borealis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria