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MYP_155569
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Basic Information
Unnamed
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
24 amino acids
C103H172N30O29
Standard
Sequence
GIGALSAKGALKGLAKGLAEHFAN
Physicochemical Analysis
2294.65 Da
9.70
1.85
1.59
0.0770
0.36
0.56
0.26
-22.64
106.25
0.0417
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
939.98
-9.62
32.0
32.0
79.0
162.0
2.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0042731 VERIFIED: YES
Provenance & Taxonomy
Bombina variegata [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus Cowan 1
14 μM
MIC
PMID8223491 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8223491/
RECORD: Rec_0197644 VERIFIED: YES
Provenance & Taxonomy
Bombina variegata [Animal]
Bombinin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
PaperM. Simmaco et al. / Biochimica et Biophysica Acta 1788 (2009) 1551-1555. Bombinins, antimicrobial peptides from Bombina species Evidence URLhttps://www.uniprot.org/uniprotkb/P01505/entry
RECORD: Rec_0246107 VERIFIED: NO
Provenance & Taxonomy
Bombina variegata [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://www.uniprot.org/uniprotkb/P01505/entry
RECORD: Rec_0274383 VERIFIED: YES
Provenance & Taxonomy
Amphibia [Animal]
Bombinin
8292
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID8454635 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8454635/
RECORD: Rec_0282734 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 45.8%, E 0.0%, T 37.5%, C 16.7% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Anti-Gram-positive Cytotoxic Anti-Gram-negative
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
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