Peptide Database

Peptide NameBeta-defensin 14 (24-45) [33,40,41A]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC100H182N38O31

DescriptionStandard

        LGKEEQIGRASNSGRKAARKKK
    

Molecular Weight2412.75 Da

Isoelectric Point (pI)11.12

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.55

Charge Density (pH 7.0) 0.2619

GRAVY Index-1.64

Hydrophobic Moment 0.78

Boman Index-0.58

Instability Index29.26

Aliphatic Index 49.09

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1191.46

LogP -16.08

H-bond Donors 43.0

H-bond Acceptors 37.0

Rotatable Bonds 92.0

Heavy Atoms 169.0

Ring Count 0.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0181164 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetPseudomonas aeruginosa PAO1

Activity50 μg/mL

MethodMBC

RECORD: Rec_0308513 VERIFIED: YES