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MYP_155551
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Basic Information
DV3(419-447)
Antimicrobial
Antiviral
Antiviral ▸ Anti-Flavivirus ▸ Anti-Dengue virus
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Standard
29 amino acids
C139H209N35O39S
Standard
Sequence
AWDFGSVGGVLNSLGKMVHQIFGSAYTAL
Physicochemical Analysis
3026.42 Da
6.79
-0.12
-0.36
-0.0041
0.57
0.65
0.38
13.77
94.14
0.1379
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1173.24
-10.68
41.0
41.0
96.0
214.0
6.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0108285 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-DENV Entry inhibition
Dengue 4 virus (DENV4) | BHK-21 cells
1.5 μM
IC90
Mammalian: 4.4 h; Yeast: >20 h; E. coli: >10 h
PaperPeptide inhibitors of flavivirus entry derived from the E protein stem. | Schmidt AG, Yang PL, Harrison SC. | J Virol. 2010 Dec;84(24):12549-54. | DOI:10.1128/JVI.01440-10 | PMID:20881042 PMID20881042 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20881042/
RECORD: Rec_0131586 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 20881042 PMID20881042 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20881042/
RECORD: Rec_0142703 VERIFIED: YES
Provenance & Taxonomy
Dengue virus 2 [Virus]
Virus-derived peptide
11060;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Dengue 2 virus (Virus entry); BHK-21
2 μM
IC90
PaperPeptide inhibitors of flavivirus entry derived from the E protein stem. | Schmidt AG, Yang PL, Harrison SC. | J Virol. 2010 | PMID:20881042 PMID20881042 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20881042/
RECORD: Rec_0146773 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-DENV Entry inhibition
Dengue 2 virus (DENV2) | BHK-21 cells
2 μM
IC90
Mammalian: 4.4 h; Yeast: >20 h; E. coli: >10 h
PaperPeptide inhibitors of flavivirus entry derived from the E protein stem. | Schmidt AG, Yang PL, Harrison SC. | J Virol. 2010 Dec;84(24):12549-54. | DOI:10.1128/JVI.01440-10 | PMID:20881042 PMID20881042 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20881042/
RECORD: Rec_0153845 VERIFIED: YES
Provenance & Taxonomy
Dengue virus 3 [Virus]
Virus-derived peptide
11069;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Dengue 3 virus (Virus entry); BHK-21
4 μM
IC90
PaperPeptide inhibitors of flavivirus entry derived from the E protein stem. | Schmidt AG, Yang PL, Harrison SC. | J Virol. 2010 | PMID:20881042 PMID20881042 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20881042/
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