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MYP_155532
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Basic Information
FLP-7-3
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Standard
11 amino acids
C55H91N17O16S2
Standard
Sequence
SPMERSAMVRF
Physicochemical Analysis
1310.55 Da
9.31
0.46
0.25
0.0421
-0.28
0.19
-0.17
82.13
35.45
0.0909
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
547.09
-5.45
20.0
19.0
42.0
90.0
2.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001246 VERIFIED: YES
Provenance & Taxonomy
Caenorhabditis elegans [Animal]
FLP-7
6239
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide Neuromodulator Receptor modulation
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for FLP-7-3 (Caenorhabditis elegans): PMID 33078707,20806053 PMID33078707;20806053 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33078707/
RECORD: Rec_0194592 VERIFIED: YES
Provenance & Taxonomy
Caenorhabditis elegans [Animal]
FMRFamide related peptide
6239
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
RFamide Neuropeptide Neuromodulator
PMID20806053 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20806053/
RECORD: Rec_0268572 VERIFIED: YES
Provenance & Taxonomy
Caenorhabditis elegans [Animal]
FLP-7
6239
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide Neuromodulator Receptor modulation
and activating the npr-22 receptor which leads to induction of the atgl-1 lipase and subsequent fat loss (PubMed:33078707)
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for FLP-7-3 (Caenorhabditis elegans): PMID 33078707,20806053 PMID33078707;20806053 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33078707/
RECORD: Rec_0312925 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0323243 VERIFIED: NO
Provenance & Taxonomy
Caenorhabditis elegans [Animal]
6239
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide