Peptide Database

Peptide NameBuforin II

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Binding / Molecular interaction ▸ Binding activity

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Anti-endotoxin

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC106H184N40O26

DescriptionStandard

        TRSSRAGLQFPVGRVHRLLRK
    

Molecular Weight2434.85 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)5.48

Net Charge (pH 7.4) 5.24

Charge Density (pH 7.0) 0.2612

GRAVY Index-0.64

Hydrophobic Moment 0.81

Boman Index-0.36

Instability Index84.20

Aliphatic Index 88.10

Aromaticity 0.0476

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1104.51

LogP -12.38

H-bond Donors 42.0

H-bond Acceptors 33.0

Rotatable Bonds 82.0

Heavy Atoms 172.0

Ring Count 3.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0418502 VERIFIED: YES

Provenance & Taxonomy

OrganismSphaenorhynchus lacteus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus 36055

Activity100 μM

MethodED50

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