‹ ›
MYP_155514
← PREVIOUS NEXT → BACK
Basic Information
Buforin II
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Binding / Molecular interaction ▸ Binding activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Anti-endotoxin
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
21 amino acids
C106H184N40O26
Standard
Sequence
TRSSRAGLQFPVGRVHRLLRK
Physicochemical Analysis
2434.85 Da
12.00
5.48
5.24
0.2612
-0.64
0.81
-0.36
84.20
88.10
0.0476
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1104.51
-12.38
42.0
33.0
82.0
172.0
3.0
21.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0402027 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Buforin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer Antiparasitic
Cryptococcus neoformans
1 μg/mL
MIC
PaperA novel antimicrobial peptide from Bufo bufo gargarizans.
RECORD: Rec_0405422 VERIFIED: YES
Provenance & Taxonomy
Bufo gargarizans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Serratia sp.
4 μg/mL
MIC
PMID8573171 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8573171/
RECORD: Rec_0410554 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HIV-1 Entry inhibition
HIV-1 IIIB | CEM-SS cells
41.1 μM
EC50
Mammalian: 7.2 h; Yeast: >20 h; E. coli: >10 h
PaperIdentification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database. | Wang G, Watson KM, Peterkofsky A, Buckheit RW Jr. | Antimicrob Agents Chemother. 2010 Mar;54(3):1343-6. | DOI:10.1128/AAC.01448-09 | PMID:20086159 PMID20086159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20086159/
RECORD: Rec_0413160 VERIFIED: YES
Provenance & Taxonomy
Bufo gargarizans [Animal]
Bufo Bufo Gargarizans
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
U-937
90-95 μg/mL
IC50
PMID21403917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21403917/
RECORD: Rec_0417070 VERIFIED: YES
Provenance & Taxonomy
Bufo gargarizans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas putida
2 μg/mL
MIC
PMID8573171 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8573171/
FIRST PREV 1 ... 11 12 13 14 NEXT LAST
Showing 5 records on this page · Page 13 of 14