Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length159 amino acids

Chemical FormulaC757H1196N222O217S6

DescriptionStandard

        MKISSNGLAVLKYFENCHLKAYPDPATGGAPWTIGWGHTGPEVKRGLVWTQKQADDALVADLARFERAVSAAVRVPLNQGQFDALVSFTYNLGEGNLKSSTLLKMVNAGNFAGAAEQFKRWNKANGKTMRGLTRRRAAEQCLFLGMGGASAIERGVAAA
    

Molecular Weight17071.34 Da

Isoelectric Point (pI)9.82

Net Charge (pH 7.0)7.67

Net Charge (pH 7.4) 7.29

Charge Density (pH 7.0) 0.0482

GRAVY Index-0.19

Hydrophobic Moment 0.81

Boman Index0.04

Instability Index29.38

Aliphatic Index 77.48

Aromaticity 0.0881

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7074.98

LogP -75.18

H-bond Donors 248.0

H-bond Acceptors 233.0

Rotatable Bonds 566.0

Heavy Atoms 1202.0

Ring Count 25.0

Amide Bonds 173.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0404573 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia phage vB_EcoM-ep3 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic