‹ ›
MYP_155458
← PREVIOUS NEXT → BACK
Basic Information
1018 or IDR-1018
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
12 amino acids
C71H125N25O13
Standard
Sequence
VRLIVAVRIWRR
Physicochemical Analysis
1536.91 Da
12.00
3.73
3.52
0.3112
0.69
0.53
-0.14
49.83
178.33
0.0833
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
646.81
-2.37
26.0
17.0
50.0
109.0
2.0
11.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0183637 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Antiplasmodial Host-defense peptide
PaperBaAMPs: the database of biofilm-active antimicrobial peptides PMID25760404 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25760404/
RECORD: Rec_0208020 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic antibiofilm peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antibiofilm Antibacterial
Staphylococcus aureus
3.255, 26.042 μM
Crystal violet assay
PaperBroad-Spectrum Anti-biofilm Peptide That Targets a Cellular Stress Response PMID24852171 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24852171/
RECORD: Rec_0208633 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus ATCC43300
4 μg/mL
MIC
PMID33770266 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33770266/
RECORD: Rec_0218409 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antibiofilm Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa PA14
PMID26525663 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26525663/
RECORD: Rec_0234709 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Innate defense regulator / cationic host-defense peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Immunomodulatory Anti-inflammatory Anti-infective
Human neutrophils
PaperInnate defense regulator peptide 1018 in wound healing and wound infection | The innate defense regulator peptides IDR-HH2, IDR-1002, and IDR-1018 modulate human neutrophil functions PMID22879874;23616580 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22879874/
FIRST PREV 1 2 3 4 5 6 ... 8 NEXT LAST
Showing 5 records on this page · Page 4 of 8