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MYP_155458
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Basic Information
1018 or IDR-1018
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
12 amino acids
C71H125N25O13
Standard
Sequence
VRLIVAVRIWRR
Physicochemical Analysis
1536.91 Da
12.00
3.73
3.52
0.3112
0.69
0.53
-0.14
49.83
178.33
0.0833
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
646.81
-2.37
26.0
17.0
50.0
109.0
2.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0026197 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic antibiofilm peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antibiofilm Antibacterial
Klebsiella pneumoniae LM21
6.51 μM
Confocal microscopy-fluorescence
PaperBroad-Spectrum Anti-biofilm Peptide That Targets a Cellular Stress Response PMID24852171 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24852171/
RECORD: Rec_0028483 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic antibiofilm peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antibiofilm Antibacterial
Acinetobacter baumannii
1.302, 6.51 μM
Crystal violet assay
PaperBroad-Spectrum Anti-biofilm Peptide That Targets a Cellular Stress Response PMID24852171 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24852171/
RECORD: Rec_0038600 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antibiofilm Anti-Gram-positive Anti-Gram-negative
Escherichia coli 0157
PMID26525663 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26525663/
RECORD: Rec_0044770 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Immunomodulatory peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antimycobacterial Immunomodulatory
Mycobacterium tuberculosis H37Rv
5400 μg/mL
MIC
PMID23555622 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23555622/
RECORD: Rec_0060223 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic antibiofilm peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antibiofilm Antibacterial
Escherichia coli
5.208, 6.51 μM
Crystal violet assay
PaperBroad-Spectrum Anti-biofilm Peptide That Targets a Cellular Stress Response PMID24852171 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24852171/
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