Peptide Database

Peptide NamePaneth cell-specific alpha-defensin 12

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length98 amino acids

Chemical FormulaC437H737N137O141S9

DescriptionStandard

        MRTLALLASLLLLVLHAQTQNLEKADDQVSAQDQPGAEVQDMTISFAGDKRSARGASKGITGTATCTCRHSNSCLSHERGSGMCISKKGKAYKLCCLR
    

Molecular Weight10454.95 Da

Isoelectric Point (pI)9.05

Net Charge (pH 7.0)4.71

Net Charge (pH 7.4) 4.23

Charge Density (pH 7.0) 0.0480

GRAVY Index-0.24

Hydrophobic Moment 0.77

Boman Index-0.07

Instability Index24.25

Aliphatic Index 79.80

Aromaticity 0.0204

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4524.07

LogP -58.83

H-bond Donors 166.0

H-bond Acceptors 158.0

Rotatable Bonds 362.0

Heavy Atoms 724.0

Ring Count 6.0

Amide Bonds 105.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0224520 VERIFIED: YES

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyDefensin

Tax ID9796

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic Non-ribosomal