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MYP_155403
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Basic Information
Hc-CATH
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
30 amino acids
C171H300N52O34
Standard
Sequence
KFFKRLLKSVRRAVKKFRKKPRLIGLSTLL
Physicochemical Analysis
3628.54 Da
12.00
11.75
11.54
0.3918
-0.27
0.99
-0.30
25.80
113.67
0.1000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1450.76
-8.44
55.0
46.0
131.0
257.0
4.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0072259 VERIFIED: YES
Provenance & Taxonomy
Hydrophis cyanocinctus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer Antifungal
Escherichia coli ATCC 25922(400 Mm NaCl
4.69 μg/mL
MIC
PMID26013823 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26013823/
RECORD: Rec_0072669 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Hydrophis cyanocinctus [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral Anti-inflammatory
Pseudomonas aeruginosa ATCC 27853
5.2-10.3 μM
MIC
PaperIdentification and Characterization of the First Cathelicidin from Sea Snakes with Potent Antimicrobial and Anti-inflammatory Activity, and Special Mechanism.
RECORD: Rec_0077016 VERIFIED: YES
Provenance & Taxonomy
Hydrophis cyanocinctus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer Antifungal
Staphylococcus aureus 5
4.69 μg/mL
MIC
PMID26013823 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26013823/
RECORD: Rec_0077277 VERIFIED: YES
Provenance & Taxonomy
Hydrophis cyanocinctus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer Antifungal
Pseudomonas aeruginosa 1
37.50 μg/mL
MIC
PMID26013823 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26013823/
RECORD: Rec_0077340 VERIFIED: YES
Provenance & Taxonomy
Hydrophis cyanocinctus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer Antifungal
Stenotrophomonas maltophilia 2
9.38 μg/mL
MIC
PMID26013823 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26013823/
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