Peptide Database

Peptide NameDrosophila defensin

Function Ontology

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Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC187H288N56O54S6

DescriptionStandard

        ATCDLLSKWNWNHTACAAHCLTKGFKGGYCSDKAVCVCRN
    

Molecular Weight4377.02 Da

Isoelectric Point (pI)8.65

Net Charge (pH 7.0)2.91

Net Charge (pH 7.4) 2.52

Charge Density (pH 7.0) 0.0727

GRAVY Index-0.14

Hydrophobic Moment 0.52

Boman Index0.02

Instability Index21.97

Aliphatic Index 56.25

Aromaticity 0.1000

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1778.39

LogP -20.62

H-bond Donors 69.0

H-bond Acceptors 65.0

Rotatable Bonds 140.0

Heavy Atoms 303.0

Ring Count 8.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0082196 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila rhopaloa [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)